Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice
نویسندگان
چکیده
منابع مشابه
Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice
Slc17a5-/- mice represent an animal model for the infantile form of sialic acid storage disease (SASD). We analyzed genetic and histological time-course expression of myelin and oligodendrocyte (OL) lineage markers in different parts of the CNS, and related this to postnatal neurobehavioral development in these mice. Sialin-deficient mice display a distinct spatiotemporal pattern of sialic acid...
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ژورنال
عنوان ژورنال: Experimental Neurology
سال: 2017
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2017.02.009